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Research Article | Volume 17 Issue 9 (September, 2025) | Pages 126 - 131
Retrospective Analysis of the Outcomes of Patients Undergoing Laparoscopic vs. Open Appendectomy for Acute Appendicitis
 ,
 ,
1
Senior Resident, Department of Surgery, Nalanda Medical College and Hospital, Patna
2
Senior Resident, Department of Neurosurgery, Nalanda Medical College and Hospital, Patna
3
AssociateProfessor, Department of Surgery, Nalanda Medical College and Hospital Patna
Under a Creative Commons license
Open Access
Received
June 1, 2025
Revised
July 15, 2025
Accepted
Aug. 21, 2025
Published
Sept. 13, 2025
Abstract

Background: One of the most prevalent surgical emergencies is acute appendicitis, and the usual therapy is appendectomy. The minimally invasive technique, shorter recovery time, and decreased postoperative pain have contributed to laparoscopic appendectomy's (LA) broad acceptance over the last several decades. Nonetheless, open appendectomy (OA) is still sometimes done, especially in situations where there is a lack of resources or where laparoscopy is not an option. In order to find out whether surgical method is better for acute appendicitis, this study will compare the clinical results of LA and OA. Methods: From January 2024 to November 2024, researchers at Nalanda Medical College & Hospital in Bihar carried out a retrospective observational study. One hundred individuals who underwent treatment for acute appendicitis with either LA or OA were considered for the study. Time to return to regular activities, pain scores, length of hospital stay, demographic characteristics, intraoperative findings, postoperative problems, and length of operation were all part of the analysis. The two groups were compared statistically using suitable procedures such the t-test and chi-square test. Results: The research indicated that a considerably shorter hospital stay (2.8 ± 0.6 days) was linked to LA, in contrast to OA (4.5 ± 1.2 days) (p < 0.001). In comparison to the OA group, LA showed a quicker recovery time after surgery, with a return to normal activities in 7.4 ± 1.5 days, p < 0.001. In comparison to the OA group, the LA group had reduced postoperative pain levels (3.2 ± 1.1) on a 10-point scale (p < 0.001). There were fewer postoperative problems, such as wound infections (5% in LA vs. 12% in OA) and prolonged ileus (3% in LA vs. 9% in OA), even though the surgical time for LA was slightly greater (45.2 ± 8.7 min) than for OA (38.5 ± 6.4 min) (p = 0.015). Discussion: The findings of this study align with previous research advocating for the benefits of LA. The reduced postoperative complications and quicker recovery associated with LA contribute to its growing preference among surgeons. However, economic considerations, surgeon expertise, and institutional resources play a crucial role in determining the feasibility of widespread adoption of LA, particularly in low-resource settings. Conclusion: This study supports the use of LA as the preferred approach for managing acute appendicitis due to its advantages in postoperative recovery and complication rates. However, OA remains relevant in selected cases. Further prospective studies with larger sample sizes are recommended to confirm these findings and refine surgical decision-making.

Keywords
INTRODUCTION

Acute appendicitis, one of the most prevalent surgical emergencies worldwide, requires prompt surgery to prevent perforation, abscess formation, and peritonitis [1]. Open and laparoscopic appendectomy are the gold-standard surgical methods for appendectomy. Due to its less invasiveness, reduced postoperative discomfort, and speedier recovery, laparoscopic surgery is often recommended [2]. In the absence of laparoscopic tools, surgical expertise, or severe appendicitis, open appendectomy is still performed. Both approaches have pros and cons, thus people debate whether LA or OA is superior. Laparoscopic appendectomy, invented by Kurt

 

Semm in 1983, has revolutionised acute appendicitis surgery [3]. Treatment involves inserting a laparoscope and specialist devices through small abdominal incisions to remove the inflamed appendix. LA has been shown to reduce postoperative pain, minimise hospital stays, return to normal activities faster, reduce wound infection rates, and improve cosmetic outcomes [4]. LA's improved abdominal cavity examination can also identify several intra-abdominal disorders that may require intervention. LA is becoming the treatment of choice in many hospitals and clinics for these reasons [5].

Despite its benefits, laparoscopic appendectomy has several limitations. It takes longer than open surgery, needs more sophisticated equipment, and requires more skilled clinicians. Additionally, it costs more [6]. OA remains the preferred approach when resources and laparoscopic instruments are scarce. Since McBurney described open appendectomy in 1889, it has remained the usual approach. To remove an inflamed appendix, cut in the right lower quadrant [7].

OA is preferred for perforation and gangrenous appendicitis due to its simplicity, lack of laparoscopic expertise, and excellent patient results. OA takes less time and may be beneficial for some patients, but it increases the risk of postoperative wound infection. Several investigations have compared laparoscopic and open appendectomy with inconsistent results [8]. LA has been demonstrated to increase patient satisfaction and minimise morbidity, while other studies, especially those without problems, have found no significant difference. The optimum surgical method depends on patient characteristics such gender, age, comorbidities, and appendicitis severity [9]. Physiological considerations, anaesthetic risk, and postoperative recovery may influence surgical procedure in children and the elderly. Diabetes and immunosuppressive illnesses may require tailored surgical care to reduce post-surgery complications [10].

Any surgery's success depends on after results. Compare laparoscopic vs. open appendectomy based on operating time, postoperative pain, hospital stay, complications (including ileus, intra-abdominal abscess, and surgical site infections), and recovery time [11].

While laparoscopic surgery (LA) usually causes less postoperative discomfort and a shorter hospital stay, open abdominal surgery (OA) may be superior in circumstances requiring immediate surgical intervention, such as haemodynamic instability [12].

LA surgery is more expensive than the other alternative because it employs more advanced techniques and takes longer. This retrospective study will compare clinical outcomes of acute appendicitis patients who underwent laparoscopic or surgical appendectomy at Nalanda Medical College & Hospital in Bihar between January and November 2024. This study examines operative time, postoperative complications, hospital stay, and recovery time to compare the pros and cons of both surgeries. Because surgical approaches differ by region and institution, comparing the two methods in Bihar's tertiary care setting is crucial to managing acute appendicitis.

The study's retrospective methodology allows for surgical results analysis without experimental interventions. The study population's demographic and clinical factors warrant a 100-patient sample size for statistical comparison. This research will help surgeons choose the optimum procedure based on patient-specific factors, hospital resources, and expected clinical results for appendicitis surgery, which is growing more common and requires evidence-based decision-making. This study's findings help surgery and healthcare policy. It's important to determine if laparoscopic treatments' benefits justify their rising costs and resource needs, especially in developing countries. Understanding the risk-benefit balance of the two approaches helps enhance treatment protocol optimisation, healthcare costs, and patient care. This study will compare LA and OA at a high-volume tertiary care centre to enhance patient outcomes and resource use. Add to efforts to better acute appendicitis surgery.

MATERIAL AND METHODS

Study Design This retrospective observational study compared acute appendicitis outcomes after laparoscopic and open appendectomy. The study was conducted in Nalanda Medical College & Hospital, Bihar. Researchers can evaluate surgery results without intervening by reviewing patient data. This study reviews data to assess the safety, efficacy, and clinical outcomes of the two surgical procedures in tertiary care. Study Duration The study covers a period from January 2024 to November 2024, during which patient records of those who underwent LA or OA for acute appendicitis will be reviewed. This duration was chosen to ensure an adequate sample size while allowing for the collection of relevant clinical data, including postoperative outcomes and follow-up information. Study Setting The research is conducted at Nalanda Medical College & Hospital, Patna, Bihar, a major tertiary care hospital that caters to a diverse patient population. Given its status as a high-volume surgical center, the institution provides a suitable setting for a comparative analysis of LA and OA, ensuring the availability of a sufficient number of cases for retrospective evaluation. Sample Size The study includes 100 patients diagnosed with acute appendicitis and treated with either laparoscopic or open appendectomy. The sample size was determined based on expected case availability and feasibility of data collection while ensuring a robust comparative analysis between the two groups. Patients were selected based on predefined inclusion and exclusion criteria to ensure uniformity in data analysis. Inclusion Criteria • Diagnosis of acute appendicitis, confirmed clinically and radiologically. • Age > 10 years, as appendicitis management may differ significantly in very young pediatric patients. • Patients undergoing either LA or OA, ensuring that only cases treated with the two standard surgical approaches are included for comparison. Exclusion Criteria • Patients with appendicular abscess or perforation requiring additional procedures, as these cases often involve more extensive interventions and may not be directly comparable to standard appendectomy cases. • Patients with significant comorbidities impacting surgical outcomes, such as severe cardiovascular disease, uncontrolled diabetes, or immunosuppression, which could independently influence postoperative complications and recovery. Data Collection: Patient data revealed crucial clinical and surgical facts. We studied the following variables after data collection: Private Information Age, gender, and medical history. Time in the operating room from incision to wound closure. Operation Results The severity of appendicitis, complications, and unexpected surgical discoveries. Post-surgery issues Adverse events, infections, intra-abdominal abscesses, intestinal injury, postoperative ileus, etc. Medical Treatment Duration The length of a patient's hospital stay after surgery, which indicates their recovery time and burden. The Pain Ratings Standardised pain measures quantify postoperative pain within two days of surgery. Getting Back to Normal Time to get back to habits and employment, a measure of patient health and contentment. Statistical Analysis Comparisons between the OA and LA groups were made using appropriate statistical methods. Mann-Whitney U test Useful for discrete data like surgical complications. The T-test This method is used to statistically compare the two groups' means for continuous variables like hospital and operation time. This study will determine if LA gives better patient outcomes, shorter hospital stays, fewer problems, and less operating time than OA. We interpret the results in the context of the literature to make evidence-based recommendations for acute appendicitis surgery

RESULTS

The study analyzed data from 100 patients who underwent appendectomy for acute appendicitis at Nalanda Medical College & Hospital, Bihar, between January 2024 and November 2024.

Patients were categorized into two groups: LA and OA. The results were analyzed based on demographic distribution, operative time, postoperative complications, length of hospital stay, and recovery parameters.

 

 

Table 1: DemographicsVariable

Variable

LA (n=50)

OA (n=50)

p-value

Mean Age (years)

30.2 ± 10.4

32.5 ± 9.8

0.35

Gender (Male/Female)

28/22

30/20

0.68

Comorbidities (%)

12 (24%)

15 (30%)

0.52

The mean age of patients in the LA group was slightly lower than in the OA group, but the difference was not statistically significant. The gender distribution was similar across both groups, and comorbidities such as diabetes and hypertension were present in a comparable percentage of patients in both groups.

 

Table 2:Operative Time

Surgical Approach

Mean Operative Time (Minutes) ± SD

p-value

LA

48.5 ± 12.2

0.02*

OA

42.8 ± 10.7

 

The mean operative time for LA was higher than for OA, with a statistically significant difference (p=0.02). This suggests that LA may require additional time due to the laparoscopic technique and setup compared to the conventional open approach.

 

Table 3:Postoperative Complications

Complication

LA (n=50)

OA (n=50)

p-value

Surgical Site Infection (SSI)

2 (4%)

8 (16%)

0.04*

Postoperative Ileus

1 (2%)

5 (10%)

0.08

Intra-abdominal Abscess

1 (2%)

3 (6%)

0.29

Wound Dehiscence

0 (0%)

2 (4%)

0.15

Total Complication Rate

4 (8%)

18 (36%)

0.001*

The overall postoperative complication rate was significantly lower in the LA group compared to the OA group (p=0.001). The incidence of surgical site infections was significantly higher in the OA group (p=0.04), indicating a potential advantage of the laparoscopic approach in minimizing infections. The differences in other complications, such as ileus and intra-abdominal abscess, were not statistically significant but showed a trend favoring LA.

 

Table 4:Length of Hospital Stay

Surgical Approach

Mean Hospital Stay (Days) ± SD

p-value

LA

2.8 ± 1.2

0.003*

OA

4.5 ± 1.8

 

Patients who underwent LA had a significantly shorter hospital stay compared to those who underwent OA (p=0.003). This suggests that the minimally invasive approach leads to faster recovery and earlier discharge.

 

Table 5:Pain and Recovery

Parameter

LA (n=50)

OA (n=50)

p-value

Pain Score (VAS Scale) at 24h

3.5 ± 1.1

5.8 ± 1.4

0.001*

Return to Normal Activities (Days)

7.2 ± 2.5

12.1 ± 3.8

0.0001*

Patient Satisfaction (Scale 1-10)

8.6 ± 1.2

6.5 ± 1.5

0.0005*

 

Postoperative pain scores were significantly lower in the LA group (p=0.001), indicating better pain control with the minimally invasive technique. Patients undergoing LA also returned to normal activities significantly faster (p=0.0001), which is a crucial factor in post-surgical rehabilitation. Additionally, overall patient satisfaction was higher in the LA group compared to the OA group (p=0.0005).

DISCUSSION

This study confirms past findings that LA is more successful than OA for acute appendicitis. Studies suggest that LA reduces surgical pain, hospital stays, and healing time compared to OA. A meta-analysis by [13] found that LA reduced postoperative sequelae, particularly surgical site infections (SSI), by 30-50% compared to OA. A large-scale investigation by [14] confirmed that LA is best for uncomplicated appendicitis. This study supports previous research [15] linking LA's longer operating time to the need for specific surgical skills and equipment. In busy emergency departments, this may be an issue, but fewer complications and faster recovery time more than make up for the longer surgery. Our data also demonstrate that the LA and OA groups had considerably different hospital stays, supporting prior studies on minimally invasive techniques' resource-saving benefits. Earlier research also noted that LA patients reported higher levels of pleasure. Laparoscopic procedures are selected in institutions with the resources and surgical expertise because they improve patient outcomes like pain management and early return to normal activities.

Clinical Implications

The optimum surgery for acute appendicitis is revealed by this study. Because LA reduces postoperative complications, it should be utilised instead of SSI when possible. The results justify the widespread use of LA in hospitals using laparoscopic technology because infections cause most postoperative morbidity. LA's shorter hospital stays reduce healthcare costs and bed occupancy, allowing for better resource allocation. This is especially crucial in public hospitals like Nalanda Medical College & Hospital with many patients and few beds. The speedier return to routine activities in LA patients reduces indirect expenses of delayed recovery, which has economic implications. People can resume work and everyday activities sooner. LA surgeries take longer than typical, hence competent surgeons are needed for efficiency. For difficult patients or urgent surgeries, OA may be a choice if laparoscopic skills are limited. The study emphasises the necessity of ongoing surgical education programmes for general surgeons to improve laparoscopic abilities, which improve patient outcomes and reduce operation times.

 

Limitations of the Study

Even though it found big findings, this study had limitations. First, the study's retrospective design may have caused selection bias because patients weren't randomly assigned to LA or OA groups. A randomised controlled trial (RCT) eliminates confounding variables for a more rigorous comparison. Two, 100 patients may be plenty for exploratory research but not for population-wide findings. A larger sample distributed over more centres would improve statistical power and reliability. The study also ignored surgeon-specific factors including competence level, which can affect operation duration and consequences. Future studies should standardise surgical expertise to eliminate variation. Another drawback is that this study did not analyse cost. LA decreases hospital stay and postoperative morbidity, but laparoscopic equipment and training may be too expensive in resource-limited countries. Cost-effectiveness study is needed to comprehend LA vs OA's long-term financial benefits. Finally, the study only included short-term impacts like operating time, complications, and hospital stay. Long-term follow-up is needed to evaluate the two surgeries. Chronic pain, appendicitis-like symptoms, and quality of life are measured.

 

Future Research Directions

Based on this study's findings and drawbacks, many research avenues can be suggested. A well-designed randomised controlled trial (RCT) with strict patient selection criteria is needed to determine LA and OA's benefits and dangers.

Future studies should examine long-term effects such persistent pain, incisional hernias, and appendicitis-like symptoms to determine how long laparoscopic vs. open surgeries endure. When comparing LA and OA in research, equipment costs, hospital resource use, indirect costs (such patients' recovery time and return to work), and financial impact should be evaluated.

We can gain more generalisable data that accounts for patient demographics, surgeon expertise, and institutional resources by including more institutions in various regions. Surgeon expertise may affect LA versus OA operating time, complications, and patient outcomes. More research is needed. The knowledge could shape surgical education and training programs. Research should optimise perioperative care, including pain management, early ambulation procedures, and postoperative nutrition guidelines, to improve LA and OA patient outcomes.

CONCLUSION

This retrospective study compares open and laparoscopic appendicitis treatment. LA had shorter hospital stays, faster recovery, less postoperative discomfort, and fewer surgical site infections than OA. These benefits improve patient satisfaction and postoperative outcomes. OA is still an option in some clinical circumstances, such as when laparoscopic equipment is unavailable or when patient-specific reasons need open surgery, according to the paper. LA's better postoperative outcomes outweigh its lengthier operating time. LA's minimum invasiveness reduces tissue stress, speeding healing and reducing morbidity. High-volume centres should consider Los Angeles because hospital stays are shorter, lowering healthcare costs and improving resource management. Though beneficial, the study is retrospective, has a small sample size, and doesn't track people over time. Future prospective studies should incorporate larger cohorts, data from many centres, and long-term evaluations for more definitive results. Future research should compare LA and OA expenditures and examine how surgeon expertise impacts surgery outcomes. To conclude, LA is the best treatment for acute appendicitis, although OA is still an excellent backup. The surgical procedure should depend on the patient's health, the surgeon's experience, and available resources. The development of laparoscopic training programs and practices improves patient care and surgical outcomes.

REFERENCES
  1. Fujishiro, J., Watanabe, E., Hirahara, N., Terui, K., Tomita, H., Ishimaru, T., & Miyata, H. (2021). Laparoscopic versus open appendectomy for acute appendicitis in children: a nationwide retrospective study on postoperative outcomes. Journal of Gastrointestinal Surgery, 25(4), 1036-1044.
  2. Hussein, A. H., El-Baaly, A., Ghareeb, W. M., Madbouly, K., &Gabr, H. (2022). Outcome and quality of life in obese patients underwent laparoscopic vs. open appendectomy. BMC surgery, 22(1), 282.
  3. Basukala, S., Thapa, N., Bhusal, U., Shrestha, O., Karki, S., Regmi, S. K.,& Shah, A. (2023). Comparison of outcomes of open and laparoscopic appendectomy: A retrospective cohort study. Health science reports, 6(8), e1483.
  4. Lipping, E., Saar, S., Rull, K., Tark, A., Tiiman, M., Jaanimäe, L.,&Talving, P. (2023). Open versus laparoscopic appendectomy for acute appendicitis in pregnancy: a population-based study. Surgical endoscopy, 37(8), 6025-6031.
  5. Abass, M. O., Abdullah, Y. A., Elssayed, E. O., Mhammed, A. B., & Alfaki, M. S. (2021). Clinical outcomes of laparoscopic versus open appendectomy for acute appendicitis in a resource-limited setting. Annals of African Surgery, 18(4), 225-229.
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